The Relationship between the Bcl-2/Bax Proteins and the Mitochondria-Mediated Apoptosis Pathway in the Differentiation of Adipose-Derived Stromal Cells into Neurons

Wang, Quanquan; Zhang, Lili; Yuan, Xiaodong; Ou, Ya; Zhu, Xuhong; Cheng, Zanzan; Zhang, Pingshu; Wu, Xiaoying; Meng, Yan; Zhang, Liping

doi:10.1371/journal.pone.0163327

Public

The Relationship between the Bcl-2/Bax Proteins and the Mitochondria-Mediated Apoptosis Pathway in the Differentiation of Adipose-Derived Stromal Cells into Neurons

Published in PLoS ONE • Oct 5, 2016

Authors:

Quanquan Wang

Lili Zhang

Xiaodong Yuan

Abstract

Our objective is to study the relationship between the regulatory proteins Bcl-2/Bax and mitochondria-mediated apoptosis during the differentiation of adipose-derived stromal cells (ADSCs) into neurons. Immunocytochemistry and western blotting showed that the cells weakly expressed neuron-specific e...

Subject

Apoptosis

Mitochondrion

Cell biology

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