Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study

Raza Ali, H.; Chlon, Leon; D.P. Pharoah, Paul; Markowetz, Florian; Caldas, Carlos

doi:10.1371/journal.pmed.1002194

Public

Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study

Published in PLoS Medicine • Dec 13, 2016

Authors:

H. Raza Ali

Leon Chlon

Paul D.P. Pharoah

Abstract

BACKGROUND: Immune infiltration of breast tumours is associated with clinical outcome. However, past work has not accounted for the diversity of functionally distinct cell types that make up the immune response. The aim of this study was to determine whether differences in the cellular composition o...

Subject

Immune system

Breast cancer

Hazard ratio

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