Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease

Lee, James; Biasci, Daniele; Roberts, Rebecca; B. Gearry, Richard; Mansfield, John; Ahmad, Tariq; J. Prescott, Natalie; Satsangi, Jack; C. Wilson, David; Jostins, Luke; A. Anderson, Carl; A. Traherne, James; Lyons, Paul; Parkes, Miles; G. C. Smith, Kenneth

doi:10.1038/ng.3755

Public

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease

Published in Nature Genetics • Jan 9, 2017

Authors:

James Lee

Daniele Biasci

Rebecca Roberts

Abstract

James Lee, Kenneth Smith and colleagues report a within-cases genome-wide association analysis for Crohn's disease to identify genetic loci specifically associated with disease severity and outcome. They find four loci associated with prognosis, none of which is associated with susceptibility to Cro...

Subject

Disease

Genome-wide association study

Biology

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