Long noncoding RNA CRNDE functions as a competing endogenous RNA to promote metastasis and oxaliplatin resistance by sponging miR-136 in colorectal cancer

Gao, Hongyan; Song, Xiaodi; Kang, Ting; Yan, Baohong; Li, Feng; Gao, Li; Ai, Liang; Liu, Xiaoni; Yu, Jie; Li, Huiqi

doi:10.2147/ott.s116178

Public

Long noncoding RNA CRNDE functions as a competing endogenous RNA to promote metastasis and oxaliplatin resistance by sponging miR-136 in colorectal cancer

Published in OncoTargets and Therapy • Jan 1, 2017

Authors:

Hongyan Gao

Xiaodi Song

Ting Kang

Abstract

Abstract: Colorectal neoplasia differentially expressed ( CRNDE ) is a novel gene recognized as a long noncoding RNA (lncRNA) that is highly elevated in colorectal cancer and many other solid tumors but its functions on metastasis and oxaliplatin (OXA) resistance are unknown. In our study, we confir...

Subject

Competing endogenous RNA

Colorectal cancer

Long non-coding RNA

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