hucMSC Exosome-Derived GPX1 Is Required for the Recovery of Hepatic Oxidant Injury.

Y, Yan; W, Jiang; Y, Tan; S, Zou; H, Zhang; F, Mao; A, Gong; H, Qian; W, Xu

doi:10.1016/j.ymthe.2016.11.019

Public

hucMSC Exosome-Derived GPX1 Is Required for the Recovery of Hepatic Oxidant Injury.

Shared by NobleBlocks on Jan 6, 2017 • 12:00 AM UTC

Authors:

Yan Y

Jiang W

Tan Y

Abstract

Exosomes are small biological membrane vesicles secreted by various cells, including mesenchymal stem cells (MSCs). We previously reported that MSC-derived exosomes (MSC-Ex) can elicit hepatoprotective effects against toxicant-induced injury. However, the success of MSC-Ex-based therapy for treatmen...

Subject

Oxidative stress

Mesenchymal stem cell

Hepatic injury

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