Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review

Wanchoo, Rimda; Karam, Sabine; N. Uppal, Nupur; S. Barta, Valerie; Deray, Gilbert; Devoe, Craig; Launay‐Vacher, Vincent; D. Jhaveri, Kenar; behalf of Cancer and Kidney International Network Workgroup on Immune Checkpoint Inhibitors, on

doi:10.1159/000455014

Public

Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review

Published in American Journal of Nephrology • Jan 1, 2017

Authors:

Rimda Wanchoo

Sabine Karam

Nupur N. Uppal

Abstract

BACKGROUND: Cancer immunotherapy, such as anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death 1 (PD-1), has revolutionized the treatment of malignancies by engaging the patient's own immune system against the tumor rather than targeting the cancer directly. These ther...

Subject

Medicine

Ipilimumab

Nivolumab

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