Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma

J. Gibson, Christopher; Coleman Lindsley, R.; Tchekmedyian, Vatche; G. Mar, Brenton; Shi, Jiantao; Jaiswal, Siddhartha; Bosworth, Alysia; Francisco, Liton; He, Jianbo; Bansal, Anita; A. Morgan, Elizabeth; S. LaCasce, Ann; S. Freedman, Arnold; C. Fisher, David; D. Jacobsen, Eric; Armand, Philippe; P. Alyea, Edwin; Koreth, John; T. Ho, Vincent; J. Soiffer, Robert; H. Antin, Joseph; Ritz, Jerome; Nikiforow, Sarah; J. Forman, Stephen; Michor, Franziska; Neuberg, Donna; Bhatia, Ravi; Bhatia, Ravi; L. Ebert, Benjamin

doi:10.1200/jco.2016.71.6712

Public

Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma

Published in Journal of Clinical Oncology • Feb 23, 2017

Authors:

Christopher J. Gibson

R. Coleman Lindsley

Vatche Tchekmedyian

Abstract

Purpose Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition characterized by somatic mutations in the blood of otherwise healthy adults. We hypothesized that in patients undergoing autologous stem-cell transplantation (ASCT) for lymphoma, CHIP at the time of ASCT would...

Subject

Medicine

Internal medicine

Autologous stem-cell transplantation

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