Next Generation Flow for highly sensitive and standardized detection of minimal residual disease in multiple myeloma

Flores‐Montero, Juan; Sanoja-Flores, Luzalba; Paiva, Bruno; Puig, Noemí; García-Sánchez, Omar; Böttcher, Sebastian; H. J. van der Velden, Vincent; Pérez-Morán, J.J.; Vídriales, María‐Belén; García‐Sánz, Ramón; Jiménez, Cristina; González, Marcos; Martínez‐López, Joaquín; Corral-Mateos, Alba; Grigore, G-E; Fluxá, Rafael; Mendonça de Pontes, Robéria; Caetano, Joana; Sędek, Łukasz; del Cañizo, MC; Bladé, Joan; Lahuerta, J-J; Aguilar, C.; Bárez, Abelardo; García‐Mateo, Aránzazu; Labrador, Jorge; Leóz, Pilar; Aguilera-Sanz, Carmen; F. San Miguel, Jesús; Mateos, MV; G.M. Durie, Brian; J. M. van Dongen, Jacques; Orfao, A

doi:10.1038/leu.2017.29

Public

Next Generation Flow for highly sensitive and standardized detection of minimal residual disease in multiple myeloma

Published in Leukemia • Jan 20, 2017

Authors:

Juan Flores‐Montero

Luzalba Sanoja-Flores

Bruno Paiva

Abstract

Flow cytometry has become a highly valuable method to monitor minimal residual disease (MRD) and evaluate the depth of complete response (CR) in bone marrow (BM) of multiple myeloma (MM) after therapy. However, current flow-MRD has lower sensitivity than molecular methods and lacks standardization. ...

Subject

Minimal residual disease

Medicine

Multiple myeloma

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