α6 Integrin (α6high)/Transferrin Receptor (CD71)low Keratinocyte Stem Cells Are More Potent for Generating Reconstructed Skin Epidermis Than Rapid Adherent Cells

Metral, Élodie; Béchetoille, Nicolas; Demarne, Frédéric; Rachidi, Walid; Damour, Odile

doi:10.3390/ijms18020282

Public

α6 Integrin (α6high)/Transferrin Receptor (CD71)low Keratinocyte Stem Cells Are More Potent for Generating Reconstructed Skin Epidermis Than Rapid Adherent Cells

Published in International Journal of Molecular Sciences • Jan 27, 2017

Authors:

Élodie Metral

Nicolas Béchetoille

Frédéric Demarne

Abstract

The epidermis basal layer is composed of two keratinocyte populations: Keratinocyte Stem cells (KSC) and Transitory Amplifying (TA) cells that arise from KSC division. Unfortunately, no specific marker exists to differ between KSC and TA cells. Here, we aimed at comparing two different methods that ...

Subject

Keratinocyte

Transferrin receptor

Flow cytometry

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