A Comparison of RNA-Seq Results from Paired Formalin-Fixed Paraffin-Embedded and Fresh-Frozen Glioblastoma Tissue Samples

Esteve‐Codina, Anna; Arpí, Oriol; Martinez‐García, Maria; Pineda, Estela; Mallo, Mar; Gut, Marta; Carrato, Cristina; Rovira, Ana; Pérez López, Raquel; Tortosa, Avelina; Dabad, Marc; Del Barco, Sonia; Heath, Simon; Bagué, Sílvia; Ribalta, Teresa; Alameda, Francesc; de la Iglesia, Núria; Balañá, Carmen; behalf of the GLIOCAT Group, on

doi:10.1371/journal.pone.0170632

Public

A Comparison of RNA-Seq Results from Paired Formalin-Fixed Paraffin-Embedded and Fresh-Frozen Glioblastoma Tissue Samples

Published in PLoS ONE • Jan 25, 2017

Authors:

Anna Esteve‐Codina

Oriol Arpí

Maria Martinez‐García

Abstract

The molecular classification of glioblastoma (GBM) based on gene expression might better explain outcome and response to treatment than clinical factors. Whole transcriptome sequencing using next-generation sequencing platforms is rapidly becoming accepted as a tool for measuring gene expression for...

Subject

RNA

Transcriptome

Gene expression

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