Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk – Combined Results from Two Screening Trials

J. Skates, Steven; H. Greene, Mark; S. Buys, Saundra; L. Mai, Phuong; Brown, Powel; Piedmonte, Marion; C. Rodriguez, Gustavo; O. Schorge, John; E. Sherman, Mark; B. Daly, Mary; F. Rutherford, Thomas; R. Brewster, Wendy; M. O’Malley, David; E. Partridge, Edward; F. Boggess, John; W. Drescher, Charles; Isaacs, Claudine; Berchuck, Andrew; M. Domchek, Susan; A. Davidson, Susan; P. Edwards, Robert; A. Elg, Steven; Wakeley, Katie; Phillips, Kelly‐Anne; K. Armstrong, Deborah; Horowitz, Ira; J. Fabian, Carol; L. Walker, Joan; M. Sluss, Patrick; J. Welch, William; M. Minasian, Lori; Horick, Nora; H. Kasten, Carol; Nayfield, Susan; S. Alberts, David; M. Finkelstein, Dianne; H. Lu, Karen

doi:10.1158/1078-0432.ccr-15-2750

Public

Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk – Combined Results from Two Screening Trials

Published in Clinical Cancer Research • Jan 31, 2017

Authors:

Steven J. Skates

Mark H. Greene

Saundra S. Buys

Abstract

Abstract Purpose: Women at familial/genetic ovarian cancer risk often undergo screening despite unproven efficacy. Research suggests each woman has her own CA125 baseline; significant increases above this level may identify cancers earlier than standard 6- to 12-monthly CA125 > 35 U/mL. Experimental...

Subject

Ovarian cancer

Medicine

Cancer

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