Efficacy of artesunate + sulphadoxine/pyrimethamine and artemether + lumefantrine and <i>dhfr</i> and <i>dhps</i> mutations in Somalia: evidence for updating the malaria treatment policy

Warsame, Marian; Hussein Hassan, Abdikarim; Mohamed Hassan, Abdillahi; Mohamed Arale, Abdulkadir; Mohamed Jibril, Ali; Abdulkadir Mohamud, Said; Barrette, Amy; Muse, Abdikarim; Essa Yusuf, Fahmi; A. Nada, Rania; Ghilan Hefzullah Amran, Jamal

doi:10.1111/tmi.12847

Public

Efficacy of artesunate + sulphadoxine/pyrimethamine and artemether + lumefantrine and dhfr and dhps mutations in Somalia: evidence for updating the malaria treatment policy

Published in Tropical Medicine & International Health • Feb 2, 2017

Authors:

Marian Warsame

Abdikarim Hussein Hassan

Abdillahi Mohamed Hassan

Abstract

OBJECTIVE: To determine the therapeutic efficacy of artesunate + sulphadoxine/pyrimethamine (AS + SP) and artemether + lumefantrine (AL), and to investigate the presence of molecular mutations associated with resistance, to inform national malaria treatment policy. METHODS: One-arm prospective studi...

Subject

Artemether/lumefantrine

Artesunate

Medicine

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