Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein

Chen, Yulei; Zhang, Siyuan; Wang, Qizhi; Zhang, Xiaobo

doi:10.1186/s13045-017-0408-0

Public

Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein

Published in Journal of Hematology & Oncology • Jan 31, 2017

Authors:

Yulei Chen

Siyuan Zhang

Qizhi Wang

Abstract

BACKGROUND: The macrophage, one of the several key immune cell types, is believed to be involved in tumorigenesis. However, the mechanism of macrophages promoting tumor progression is largely unknown. METHODS: The differentially secreted proteins of M1 and M2 macrophages were analyzed by mass spectr...

Subject

Hematology

Macrophage

Breast cancer

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