Selective serotonin reuptake inhibitors versus placebo in patients with major depressive disorder. A systematic review with meta-analysis and Trial Sequential Analysis

Christian Jakobsen, Janus; Kumar Katakam, Kiran; Schou, Anne; Hellmuth, Signe; Elkjær Stallknecht, Sandra; Leth-Møller, Katja; Iversen, Maria; Banke, Marianne; Petersen, Iggiannguaq; Louise Klingenberg, Sarah; Krogh, Jesper; Ebert, Sebastian; Timm, Anne; Lindschou, Jane; Gluud, Christian

doi:10.1186/s12888-016-1173-2

Public

Selective serotonin reuptake inhibitors versus placebo in patients with major depressive disorder. A systematic review with meta-analysis and Trial Sequential Analysis

Published in BMC Psychiatry • Feb 8, 2017

Authors:

Janus Christian Jakobsen

Kiran Kumar Katakam

Anne Schou

Abstract

BACKGROUND: The evidence on selective serotonin reuptake inhibitors (SSRIs) for major depressive disorder is unclear. METHODS: Our objective was to conduct a systematic review assessing the effects of SSRIs versus placebo, 'active' placebo, or no intervention in adult participants with major depress...

Subject

Meta-analysis

Serotonin Uptake Inhibitors

Placebo

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