Pre‐ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress‐dependent autophagy via <scp>PERK</scp> and <scp>IRE</scp>1 signalings

Feng, Dayun; Wang, Bao; Wang, Lei; Abraham, Neeta; Tao, Kai; Huang, Lu; Shi, Wei; Dong, Yushu; Qu, Yan

doi:10.1111/jpi.12395

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Pre‐ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress‐dependent autophagy via PERK and IRE1 signalings

Shared by NobleBlocks on Mar 6, 2017 • 12:00 AM UTC

Authors:

Dayun Feng

Bao Wang

Lei Wang

Abstract

Abstract Melatonin has demonstrated a potential protective effect in central nervous system. Thus, it is interesting to determine whether pre‐ischemia melatonin administration could protect against cerebral ischemia/reperfusion ( IR )‐related injury and the underlying molecular mechanisms. In this s...

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