MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinoma

Qu, Kai; Wang, Zhixin; Fan, Haining; Li, Juan; Liu, Jie; Li, Pingping; Liang, Zheyong; An, Hongli; Jiang, Yina; Lin, Qiushi; Dong, Xiaoqun; Liu, Peijun; Liu, Chang

doi:10.1038/cddis.2016.352

Public

MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinoma

Shared by NobleBlocks on Feb 9, 2017 • 12:00 AM UTC

Authors:

Kai Qu

Zhixin Wang

Haining Fan

Abstract

Abstract DNA replication is a central procedure of cell proliferation, whereas aberrant DNA replication is indicated to be a driving force of oncogenesis. Minichromosome maintenance complex component 7 (MCM7) plays an essential role in initiating DNA replication. To investigate the potential oncogen...

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