A Comprehensive Study of Chromosome 13 Abnormalities (Δ 13) in Multiple Myeloma Using High-Throughput, Array-Based Methods.

Baker, Angela; Price-Troska, Tammy; Bittner, Michael; A. Van Wier, Scott; E. Rempel, Rachel; Ahmann, Gregory; S. Pidgeon, Tyler; Mousses, Spyro; Futscher, Bernie; D. Fonseca, Rafael; D. Carpten, John

doi:10.1182/blood.v104.11.1417.1417

Public

A Comprehensive Study of Chromosome 13 Abnormalities (Δ 13) in Multiple Myeloma Using High-Throughput, Array-Based Methods.

Shared by NobleBlocks on Nov 16, 2004 • 12:00 AM UTC

Authors:

Angela Baker

Tammy Price-Troska

Michael Bittner

Abstract

Abstract Chromosome 13 abnormalities (Δ13), monosomy or deletion, are seen in greater than 50% in patients with Multiple Myeloma (MM) and are associated with poor survival and reduced response to therapy. Δ13 is suggestive of a tumor suppressor model. In this study, we use a comprehensive, high-thro...

Subject

Biology

Comparative genomic hybridization

Gene

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