Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma

Chen, Zhihong; Feng, Xi; J. Herting, Cameron; Álvarez-García, Virginia; Nie, Kai; W. Pong, Winnie; Rasmussen, Rikke; Dwivedi, Bhakti; Seby, Sandra; A. Wolf, Susanne; H. Gutmann, David; Hambardzumyan, Dolores

doi:10.1158/0008-5472.can-16-2310

Public

Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma

Published in Cancer Research • Feb 24, 2017

Authors:

Zhihong Chen

Xi Feng

Cameron J. Herting

Abstract

Abstract In glioblastoma (GBM), tumor-associated macrophages (TAM) represent up to one half of the cells of the tumor mass, including both infiltrating macrophages and resident brain microglia. In an effort to delineate the temporal and spatial dynamics of TAM composition during gliomagenesis, we us...

Subject

Microglia

Bone marrow

Population

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