Continued Benefit to Rectal Separation for Prostate Radiation Therapy: Final Results of a Phase III Trial

A. Hamstra, Daniel; Mariados, Neil; Sylvester, John; Shah, Dhiren; I. Karsh, Lawrence; Hudes, Richard; Beyer, David; Kurtzman, Steven; A. Bogart, Jeffrey; Hsi, R.A.; Kos, Michael; J. Ellis, Rodney; D. Logsdon, Mark; Zimberg, S.H.; Forsythe, Kevin; Zhang, Hong; Soffen, Edward; Francke, Patrick; Mantz, C.A.; J. Rossi, Peter; DeWeese, Theodore; Daignault‐Newton, Stephanie; W. Fischer‐Valuck, Benjamin; Chundury, Anupama; A. Gay, Hiram; Bosch, Walter; M. Michalski, Jeff

doi:10.1016/j.ijrobp.2016.12.024

Public

Continued Benefit to Rectal Separation for Prostate Radiation Therapy: Final Results of a Phase III Trial

Published in International Journal of Radiation Oncology*Biology*Physics • Dec 23, 2016

Authors:

Daniel A. Hamstra

Neil Mariados

John Sylvester

Abstract

PURPOSE: SpaceOAR, a Food and Drug Administration-approved hydrogel intended to create a rectal-prostate space, was evaluated in a single-blind phase III trial of image guided intensity modulated radiation therapy. A total of 222 men were randomized 2:1 to the spacer or control group and received 79...

Subject

Prostate

Medicine

Radiation therapy

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