The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of <i>Mycobacterium tuberculosis</i>.

J, Quigley; VK, Hughitt; CA, Velikovsky; RA, Mariuzza; NM, El-Sayed; V, Briken

doi:10.1128/mbio.00148-17

Public

The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis.

Shared by NobleBlocks on Mar 7, 2017 • 12:00 AM UTC

Authors:

Quigley J

Hughitt VK

Velikovsky CA

Abstract

The cell wall of Mycobacterium tuberculosis is composed of unique lipids that are important for pathogenesis. Indeed, the first-ever genetic screen in M. tuberculosis identified genes involved in the biosynthesis and transport of the cell wall lipid PDIM (phthiocerol dimycocerosates) as crucial for ...

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