The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of <i>Mycobacterium tuberculosis</i>

Quigley, Jeff; Keith Hughitt, V.; A. Velikovsky, Carlos; A. Mariuzza, Roy; M. El-Sayed, Najib; Briken, Volker

doi:10.1128/mbio.00148-17

Public

The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis

Published in mBio • Mar 7, 2017

Authors:

Jeff Quigley

V. Keith Hughitt

Carlos A. Velikovsky

Abstract

ABSTRACT The cell wall of Mycobacterium tuberculosis is composed of unique lipids that are important for pathogenesis. Indeed, the first-ever genetic screen in M. tuberculosis identified genes involved in the biosynthesis and transport of the cell wall lipid PDIM ( p hthiocerol dim ycocerosates) as ...

Subject

Mycobacterium tuberculosis

Microbiology

Tuberculosis

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