Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis

Zille, Marietta; S. Karuppagounder, Saravanan; Chen, Yingxin; J. Gough, Peter; Bertin, John; N. Finger, Joshua; A. Milner, Teresa; A. Jonas, Elizabeth; R. Ratan, Rajiv

doi:10.1161/strokeaha.116.015609

Public

Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis

Published in Stroke • Mar 2, 2017

Authors:

Marietta Zille

Saravanan S. Karuppagounder

Yingxin Chen

Abstract

BACKGROUND AND PURPOSE: Intracerebral hemorrhage leads to disability or death with few established treatments. Adverse outcomes after intracerebral hemorrhage result from irreversible damage to neurons resulting from primary and secondary injury. Secondary injury has been attributed to hemoglobin an...

Subject

Necroptosis

Programmed cell death

Hemin

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