Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

Shrike Zhang, Yu; Aleman, Julio; Ryon Shin, Su; Kiliç, Tuğba; Jin Kim, Duck; Ali Mousavi Shaegh, Seyed; Massa, Solange; Riahi, Reza; Chae, Sukyoung; Hu, Ning; Avcı, Hüseyin; Zhang, Weijia; Silvestri, Antonia; Sanati‐Nezhad, Amir; Manbohi, Ahmad; De Ferrari, Fabio; Polini, Alessandro; Calzone, Giovanni; Shaikh, Noor; Alerasool, Parissa; Budina, Erica; Kang, Jian; Bhise, Nupura; Ribas, João; Pourmand, Adel; Skardal, Aleksander; Shupe, Thomas; E. Bishop, Colin; R. Dokmeci, Mehmet; Atala, Anthony; Khademhosseini, Ali

doi:10.1073/pnas.1612906114

Public

Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

Published in Proceedings of the National Academy of Sciences • Mar 6, 2017

Authors:

Yu Shrike Zhang

Julio Aleman

Su Ryon Shin

Abstract

Organ-on-a-chip systems are miniaturized microfluidic 3D human tissue and organ models designed to recapitulate the important biological and physiological parameters of their in vivo counterparts. They have recently emerged as a viable platform for personalized medicine and drug screening. These in ...

Subject

Microfluidics

Modular design

Organ-on-a-chip

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