Alterations to the Gut Microbiome Impair Bone Strength and Tissue Material Properties

D Guss, Jason; W. Horsfield, Michael; F. Fontenele, Fernanda; N. Sandoval, Taylor; Luna, Marysol; Apoorva, Fnu; Lima, Svetlana; Bicalho, R.C.; Singh, Ankur; E. Ley, Ruth; C. H. van der Meulen, Marjolein; R. Goldring, Steven; J. Hernandez, Christopher

doi:10.1002/jbmr.3114

Public

Alterations to the Gut Microbiome Impair Bone Strength and Tissue Material Properties

Published in Journal of Bone and Mineral Research • Feb 28, 2017

Authors:

Jason D Guss

Michael W. Horsfield

Fernanda F. Fontenele

Abstract

Alterations in the gut microbiome have been associated with changes in bone mass and microstructure, but the effects of the microbiome on bone biomechanical properties are not known. Here we examined bone strength under two conditions of altered microbiota: (1) an inbred mouse strain known to develo...

Subject

Gut flora

Biology

Microbiome

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