Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

the ENIGMA Bipolar Disorder Working Group, for; P. Hibar, Derrek; T. Westlye, Lars; Trung Doan, Nhat; Jahanshad, Neda; Cheung, J.; R. K. Ching, Christopher; Versace, Amelia; C. Bilderbeck, Amy; Uhlmann, Anne; Mwangi, Benson; Krämer, Bernd; J. Overs, Bronwyn; B. Hartberg, Cecilie; Abé, Christoph; Dima, Danai; Grotegerd, Dominik; Sprooten, Emma; Bøen, Erlend; Jiménez, Esther; M. Howells, Fleur; Delvecchio, Giuseppe; Temmingh, Henk; Starke, Jonathan; Almeida, Jorge; Manuel Goikolea, José; Houenou, Josselin; M. Beard, Lauren; Rauer, Lisa; Abramovic, Lucija; Bonnin, M.; Francesca Ponteduro, Maria; Keil, Maria; M. Rive, Maria; Yao, Nailin; Yalın, Nefize; Najt, Pablo; G. P. Rosa, Pedro; Redlich, Ronny; Trost, Sarah; P. Hagenaars, Saskia; C. Fears, Scott; Alonso-Lana, Sílvia; G.M. van Erp, Theo; E. Nickson, Thomas; Chaim-Avancini, Tiffany; B. Meier, Timothy; Elvsåshagen, Torbjørn; K. Haukvik, Unn; H Lee, W; H. Schene, Aart; J. Lloyd, Adrian; H. Young, Allan; C. Nugent, Allison; M. Dale, Anders; Pfennig, Andrea; M. McIntosh, Andrew; Lafer, Beny; T. Baune, Bernhard; Johan Ekman, Carl; A. Zarate, Carlos; E. Bearden, Carrie; Henry, Chantal; Simhandl, Christian; McDonald, Colm; Bourne, Corin; J. Stein, Dan; H. Wolf, Daniel; M. Cannon, Dara; C. Glahn, David; J. Veltman, Dick; Pomarol‐Clotet, Edith; Vieta, Eduard; J. Canales‐Rodríguez, Erick; G. Nery, Fabiano; Duran, Fábio; F. Busatto, Geraldo; Roberts, Gloria; D. Pearlson, Godfrey; M. Goodwin, Guy; Kugel, Harald; C. Whalley, Heather; G. Ruhé, Henricus; C. Soares, Jair; M. Fullerton, Janice; Rybakowski, Janusz; Savitz, Jonathan; T Chaim, Kalil; Fatjó‐Vilas, Mar; Gerhardt Soeiro‐de‐Souza, Márcio; P. Boks, Marco; V. Zanetti, Marcus; Concepción García Otaduy, Maria; Schaufelberger, Maria; Alda, Martin; Ingvar, Martin; L. Phillips, Mary; J. Kempton, Matthew; Bauer, Michael; Landén, Mikael; Lawrence, Natalia; E.M. van Haren, Neeltje; Horn, Neil; B. Freimer, Nelson; Gruber, Oliver; R. Schofield, Peter; B. Mitchell, Philip; Kahn, R.S.; Lenroot, Rhoshel; Machado‐Vieira, Rodrigo; A. Ophoff, Roel; Sarró, Salvador; Frangou, Sophia; D. Satterthwaite, Theodore; Hájek, Tomáš; Dannlowski, Udo; Fredrik Malt, Ulrik; Arolt, Volker; F. Gattaz, Wagner; C. Drevets, Wayne; Caseras, Xavier; Agartz, Ingrid; M. Thompson, Paul; A. Andreassen, Ole

doi:10.1038/mp.2017.73

Public

Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

Published in Molecular Psychiatry • May 2, 2017

Authors:

for the ENIGMA Bipolar Disorder Working Group

Derrek P. Hibar

Lars T. Westlye

Abstract

Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understood. Structural brain differences have been associated with BD, but results from neuroimaging studies have been inconsistent. To address this, we performed the largest study to date of cortical gray ma...

Subject

Bipolar disorder

Psychology

Neuroscience

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