Local Treatment of Unresectable Colorectal Liver Metastases: Results of a Randomized Phase II Trial

J. M. Ruers, Theo; van Coevorden, Frits; J.A. Punt, Cornelis; E. N. Pierie, Jean-Pierre; Borel-Rinkes, Inne; A. Ledermann, Jonathan; J. Poston, Graeme; O. Bechstein, Wolf; Lentz, M.A.; Mauer, Murielle; Folprecht, Gunnar; Van Cutsem, Eric; Ducreux, Michel; Nordlinger, Bernard

doi:10.1093/jnci/djx015

Public

Local Treatment of Unresectable Colorectal Liver Metastases: Results of a Randomized Phase II Trial

Published in JNCI Journal of the National Cancer Institute • Jan 30, 2017

Authors:

Theo J. M. Ruers

Frits van Coevorden

Cornelis J.A. Punt

Abstract

Background: Tumor ablation is often employed for unresectable colorectal liver metastases. However, no survival benefit has ever been demonstrated in prospective randomized studies. Here, we investigate the long-term benefits of such an aggressive approach. Methods: In this randomized phase II trial...

Subject

Medicine

Hazard ratio

Clinical endpoint

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