Azole-resistant Aspergillus fumigatus harboring TR34/L98H, TR46/Y121F/T289A and TR53 mutations related to flower fields in Colombia

Álvarez, Carlos; Lavergne, Rose‐Anne; Hagen, Ferry; Morio, Florent; F. Meis, Jacques; Le Pape, Patrice

doi:10.1038/srep45631

Public

Azole-resistant Aspergillus fumigatus harboring TR34/L98H, TR46/Y121F/T289A and TR53 mutations related to flower fields in Colombia

Published in Scientific Reports • Mar 30, 2017

Authors:

Carlos Álvarez

Rose‐Anne Lavergne

Ferry Hagen

Abstract

Abstract Resistance to triazoles in Aspergillus fumigatus has been reported in azole-naive patients in Europe, Asia, Australia and North America. This resistance has been linked to fungicide-driven mutations in the cyp51A gene and its promoter region. We investigated the presence of environmental az...

Subject

Aspergillus fumigatus

Azole

Tebuconazole

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!