Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma

Perry, James; Laperrière, Normand; J. O’Callaghan, Christopher; A. Brandes, Alba; Menten, Johan; Phillips, Claire; Fay, Michael; Nishikawa, Ryo; Gregory Cairncross, J.; Roa, Wilson; Osoba, David; P. Rossiter, John; Sahgal, Arjun; W. Hirte, Hal; Laigle–Donadey, Florence; Franceschi, Enrico; Chinot, Olivier; Golfinopoulos, Vassilis; Fariselli, Laura; Wick, Antje; Feuvret, L.; Back, Michael; Tills, Michael; Winch, Chad; G. Baumert, Brigitta; Wick, Wolfgang; Ding, Keyue; Mason, Warren

doi:10.1056/nejmoa1611977

Public

Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma

Published in New England Journal of Medicine • Mar 15, 2017

Authors:

James Perry

Normand Laperrière

Christopher J. O’Callaghan

Abstract

BACKGROUND: Glioblastoma is associated with a poor prognosis in the elderly. Survival has been shown to increase among patients 70 years of age or younger when temozolomide chemotherapy is added to standard radiotherapy (60 Gy over a period of 6 weeks). In elderly patients, more convenient shorter c...

Subject

Temozolomide

Medicine

Hazard ratio

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