ARCHER: Dacomitinib (D; PF-00299804) versus erlotinib (E) for advanced (adv) non-small cell lung cancer (NSCLC)—A randomized double-blind phase III study.

Boyer, Michael; A. Jänne, Pasi; Mok, Tony; J. O’Byrne, Kenneth; Paz‐Ares, Luis; S. Ramalingam, Suresh; Liang, Jane; W. Taylor, Ian; Campbell, Alicyn; O’Connell, Joseph; P. Letrent, Stephen; Antic, Vladan

doi:10.1200/jco.2012.30.15_suppl.tps7615

Public

ARCHER: Dacomitinib (D; PF-00299804) versus erlotinib (E) for advanced (adv) non-small cell lung cancer (NSCLC)—A randomized double-blind phase III study.

Published in Journal of Clinical Oncology • May 20, 2012

Authors:

Michael Boyer

Pasi A. Jänne

Tony Mok

Abstract

TPS7615 Background: D is a highly selective irreversible small molecule inhibitor of all catalytically active members of the HER (human epidermal growth factor receptor) family of tyrosine kinases. In a randomized phase II trial in patients (pts) who had received 1–2 prior systemic therapy regimens ...

Subject

Medicine

Internal medicine

Erlotinib

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