Bupropion for the treatment of apathy in Huntington's disease: A multicenter, randomised, double-blind, placebo-controlled, prospective crossover trial.

H, Gelderblom; T, Wüstenberg; T, McLean; L, Mütze; W, Fischer; C, Saft; R, Hoffmann; S, Süssmuth; P, Schlattmann; Duijn E, van; B, Landwehrmeyer; J, Priller

doi:10.1371/journal.pone.0173872

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Bupropion for the treatment of apathy in Huntington's disease: A multicenter, randomised, double-blind, placebo-controlled, prospective crossover trial.

Shared by NobleBlocks on Mar 21, 2017 • 12:00 AM UTC

Authors:

Gelderblom H

Wüstenberg T

McLean T

Abstract

Objective To evaluate the efficacy and safety of bupropion in the treatment of apathy in Huntington's disease (HD).Methods In this phase 2b multicentre, double-blind, placebo-controlled crossover trial, individuals with HD and clinical signs of apathy according to the Structured Clinical Interview f...

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