m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

Cui, Qi; Shi, Hailing; Ye, Peng; Li, Li; Qu, Qiuhao; Sun, Guoqiang; Sun, Guihua; Lu, Zhike; Huang, Yue; Yang, Cai‐Guang; D. Riggs, Arthur; He, Chuan; Shi, Yanhong

doi:10.1016/j.celrep.2017.02.059

Public

m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

Published in Cell Reports • Mar 1, 2017

Authors:

Qi Cui

Hailing Shi

Peng Ye

Abstract

RNA modifications play critical roles in important biological processes. However, the functions of N 6 -methyladenosine (m 6 A) mRNA modification in cancer biology and cancer stem cells remain largely unknown. Here, we show that m 6 A mRNA modification is critical for glioblastoma stem cell (GSC) se...

Subject

Glioblastoma

Methylation

Carcinogenesis

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