Efficacy, long-term toxicity, and mechanistic studies of gold nanorods photothermal therapy of cancer in xenograft mice

Significance This is a systematic in vivo study of gold nanorods (AuNRs)-assisted plasmonic photothermal therapy (AuNRs-PPTT) for cancer. We have optimized the properties of our AuNRs and the conditions of PPTT to achieve maximal induction of tumor apoptosis. To examine the molecular mechanisms of a... View More