Exosomes derived from miR‐181‐5p‐modified adipose‐derived mesenchymal stem cells prevent liver fibrosis
                    <i>via</i>
                    autophagy activation

Qu, Ying; Zhang, Qidi; Cai, Xiaobo; Li, Fei; Ma, Zhenzeng; Xu, Mingyi; Lu, Lungen

doi:10.1111/jcmm.13170

Public

Exosomes derived from miR‐181‐5p‐modified adipose‐derived mesenchymal stem cells prevent liver fibrosis via autophagy activation

Shared by NobleBlocks on Apr 6, 2017 • 12:00 AM UTC

Authors:

Ying Qu

Qidi Zhang

Xiaobo Cai

Abstract

Abstract Proliferating hepatic stellate cells ( HSC s) respond to liver damage by secreting collagens that form fibrous scar tissue, which can lead to cirrhosis if in appropriately regulated. Advancement of micro RNA (mi RNA ) hepatic therapies has been hampered by difficulties in delivering mi RNA ...

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