The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine

M. Cortese‐Krott, Miriam; M. Koning, Anne; Kuhnle, Gunter; Nagy, Péter; L. Bianco, Christopher; Pasch, Andreas; A. Wink, David; M. Fukuto, Jon; A. Jackson, Alan; van Goor, Harry; R. Olson, Kenneth; Feelisch, Martin

doi:10.1089/ars.2017.7083

Public

The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine

Published in Antioxidants and Redox Signaling • Apr 11, 2017

Authors:

Miriam M. Cortese‐Krott

Anne M. Koning

Gunter Kuhnle

Abstract

SIGNIFICANCE: Oxidative stress is thought to account for aberrant redox homeostasis and contribute to aging and disease. However, more often than not, administration of antioxidants is ineffective, suggesting that our current understanding of the underlying regulatory processes is incomplete. Recent...

Subject

Organism

Interactome

Systems biology

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