Tracking the Evolution of Non–Small-Cell Lung Cancer

Jamal‐Hanjani, Mariam; A. Wilson, Gareth; McGranahan, Nicholas; J. Birkbak, Nicolai; B.K. Watkins, Thomas; Veeriah, Selvaraju; Shafi, Seema; Johnson, Diana; Mitter, Richard; Rosenthal, Rachel; Salm, Max; Horswell, Stuart; Escudero, Mickael; Matthews, Nik; Rowan, Andrew; Chambers, Tim; A. Moore, David; Turajlic, Samra; Xu, Hang; Ming Lee, Siow; Förster, Martin; Ahmad, Tanya; T. Hiley, Crispin; Abbosh, Christopher; Falzon, Mary; Borg, Elaine; Marafioti, Teresa; Lawrence, David; Hayward, Martin; Kolvekar, Shyam; Panagiotopoulos, Nikolaos; M. Janes, Sam; M. Thakrar, Ricky; Ahmed, Asia; Blackhall, Fiona; Summers, Yvonne; Shah, Rajesh; Dennis Joseph, Leena; Marie Quinn, Anne; Crosbie, Philip; Naidu, Babu; Middleton, Gary; Langman, Gerald; Trotter, Simon; Nicolson, M.; Remmen, Hardy; M. Kerr, Keith; Chetty, Mahendran; Gomersall, Lesley; A. Fennell, Dean; Nakas, Apostolos; Rathinam, Sridhar; Anand, Girija; Khan, Sajid; Russell, Peter; Ezhil, Veni; Ismail, Babikir; Irvin-Sellers, Melanie; Prakash, Vineet; Lester, J.F.; Kornaszewska, Malgorzata; Attanoos, Richard; Adams, Haydn; Davies, Helen; C. Dentro, Stefan; Tanière, Philippe; O’Sullivan, Brendan; L. Lowe, Helen; A. Hartley, John; Iles, Natasha; Bell, Harriet; Ngai, Yenting; Shaw, Jacqui; Herrero, Javier; Szállási, Zoltán; F. Schwarz, Roland; Stewart, Aengus; A. Quezada, Sergio; Le Quesne, John; Van Loo, Peter; Dive, Caroline; Hackshaw, Allan; Swanton, Charles

doi:10.1056/nejmoa1616288

Public

Tracking the Evolution of Non–Small-Cell Lung Cancer

Published in New England Journal of Medicine • Apr 26, 2017

Authors:

Mariam Jamal‐Hanjani

Gareth A. Wilson

Nicholas McGranahan

Abstract

BACKGROUND: Among patients with non-small-cell lung cancer (NSCLC), data on intratumor heterogeneity and cancer genome evolution have been limited to small retrospective cohorts. We wanted to prospectively investigate intratumor heterogeneity in relation to clinical outcome and to determine the clon...

Subject

Tracking (education)

Lung cancer

Biology

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