Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients

Chiappini, Franck; Coilly, Audrey; Kadar, Hanane; Gual, Philippe; Tran, Albert; Desterke, Christophe; Samuel, Didier; Duclos‐Vallée, Jean‐Charles; Touboul, David; Bertrand‐Michel, Justine; Brunelle, Alain; Guettier, Catherine; Le Naour, François

doi:10.1038/srep46658

Public

Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients

Published in Scientific Reports • Apr 24, 2017

Authors:

Franck Chiappini

Audrey Coilly

Hanane Kadar

Abstract

Nonalcoholic steatohepatitis (NASH) is a condition which can progress to cirrhosis and hepatocellular carcinoma. Markers for NASH diagnosis are still lacking. We performed a comprehensive lipidomic analysis on human liver biopsies including normal liver, nonalcoholic fatty liver and NASH. Random for...

Subject

Lipid metabolism

Nonalcoholic steatohepatitis

Cirrhosis

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