Overexpression of the Cytokine BAFF and Autoimmunity Risk

Steri, Maristella; Orrù, Valeria; Laura Idda, Maria; Pitzalis, Maristella; Pala, Mauro; Zara, Ilenia; Sidore, Carlo; Faà, V.; Floris, Matteo; Deiana, Manila; Asunis, Isadora; Porcu, Eleonora; Mulas, Antonella; Grazia Piras, Maria; Lobina, Monia; Lai, Sandra; Marongiu, Mara; Serra, Valentina; Marongiu, Michele; Sole, Gabriella; Busonero, Fabio; Maschio, Andrea; Cusano, Roberto; Cuccuru, Gianmauro; Deidda, Francesca; Poddie, Fausto; Farina, Gabriele; Dei, Mariano; Virdis, Francesca; Olla, Stefania; Anna Satta, Maria; Pani, Mario; Delitala, Alessandro; Cocco, Eleonora; Frau, Jessica; Coghe, Giancarlo; Lorefice, Lorena; Fenu, Giuseppe; Ferrigno, Paola; Ban, Maria; Barizzone, Nadia; Leone, Maurizio; Rosa Guerini, Franca; Piga, Matteo; Firinu, Davide; Kockum, Ingrid; Lima Bomfim, Izaura; Olsson, Tomas; Alfredsson, Lars; Suárez, Ana; Carreira, Patrícia; Jesús Castillo‐Palma, María; Marcus, Joseph; Congia, Mauro; Angius, Andrea; Melis, Maurizio; González, Antonio; E. Alarcón‐Riquelme, Marta; Martins da Silva, Berta; Marchini, Maurizio; Giovanna Danieli, Maria; Del Giacco, Stefano; Mathieu, Alessandro; Pani, Antonello; B. Montgomery, Stephen; Rosati, Giulio; Hillert, Jan; Sawcer, Stephen; D’Alfonso, Sandra; A. Todd, John; Novembre, John; R. Abecasis, Gonçalo; B. Whalen, Michael; Giovanna Marrosu, Maria; Meloni, Alessandra; Sanna, Serena; Gorospe, Myriam; Schlessinger, David; Fiorillo, Edoardo; Żołędziewska, Magdalena; Cucca, Francesco

doi:10.1056/nejmoa1610528

Public

Overexpression of the Cytokine BAFF and Autoimmunity Risk

Published in New England Journal of Medicine • Apr 26, 2017

Authors:

Maristella Steri

Valeria Orrù

Maria Laura Idda

Abstract

BACKGROUND: Genomewide association studies of autoimmune diseases have mapped hundreds of susceptibility regions in the genome. However, only for a few association signals has the causal gene been identified, and for even fewer have the causal variant and underlying mechanism been defined. Coinciden...

Subject

B-cell activating factor

Immunology

Autoimmunity

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