Identification of factors required for m <sup>6</sup> A mRNA methylation in <i>Arabidopsis</i> reveals a role for the conserved E3 ubiquitin ligase HAKAI

Růžička, Kamil; Zhang, Mi; Campilho, Ana; Bódi, Zsuzsanna; Kashif, Muhammad; Saleh, Maria‐Carla; Eeckhout, Dominique; El‐Showk, Sedeer; Li, Hongying; Zhong, Silin; De Jaeger, Geert; P. Mongan, Nigel; Hejátko, Jan; Helariutta, Ykä; G. Fray, Rupert

doi:10.1111/nph.14586

Public

Identification of factors required for m 6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI

Published in New Phytologist • May 15, 2017

Authors:

Kamil Růžička

Mi Zhang

Ana Campilho

Abstract

Summary N 6‐adenosine methylation (m 6 A) of mRNA is an essential process in most eukaryotes, but its role and the status of factors accompanying this modification are still poorly understood. Using combined methods of genetics, proteomics and RNA biochemistry, we identified a core set of mRNA m 6 A...

Subject

Arabidopsis

Ubiquitin ligase

Methylation

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