Effectiveness and safety of bedaquiline-containing regimens in the treatment of MDR- and XDR-TB: a multicentre study

Se, Borisov; Dheda, Keertan; Enwerem, Martin; Romero Leyet, Rodolfo; D’Ambrosio, Lia; Centis, Rosella; Sotgiu, Giovanni; Tiberi, Simon; C. Alffenaar, Jan‐Willem; O. Мaryandyshev, А.; Belilovski, Evgeny; Ganatra, Shashank; Skrahina, Alena; W. Akkerman, Onno; Aleksa, Alena; Amale, Rohit; Artsukevich, Janina; Bruchfeld, Judith; A. Caminero, José; Carpena Martinez, Isabel; Ruffo Codecasa, Luigi; Pretti Dalcolmo, Margareth; T. Denholm, Justin; Douglas, Paul; Duarte, Raquel; Esmail, Aliasgar; Fadul, Mohammed; Av, Filippov; Davies Forsman, Lina; Gaga, Mina; García-Fuertes, Julia-Amaranta; García-García, José-María; Gualano, Gina; Jonsson, Jerker; Kunst, Heinke; S. Y. Lau, Jillian; Lazaro Mastrapa, Barbara; Lazaro Teran Troya, Jorge; Manga, Selene; Manika, Κaterina; González Montaner, Pablo; Mullerpattan, Jai; Oelofse, Suzette; Ortelli, Martina; Palmero, Domingo; Palmieri, Fabrizio; Papalia, Antonella; Papavasileiou, Apostolos; Payen, Marie-Christine; Pontali, Emanuele; Robalo Cordeiro, Carlos; Saderi, Laura; Dorji Sadutshang, Tsetan; Sanukevich, Tatsiana; Solodovnikova, Varvara; Spanevello, Antonio; Topgyal, Sonam; Toscanini, Federica; R Tramontana, Adrian; Udwadia, Zarir; Viggiani, Pietro; White, Verónica; Zumla, Alimuddin; Battista Migliori, Giovanni

doi:10.1183/13993003.00387-2017

Public

Effectiveness and safety of bedaquiline-containing regimens in the treatment of MDR- and XDR-TB: a multicentre study

Published in European Respiratory Journal • May 1, 2017

Authors:

Borisov Se

Keertan Dheda

Martin Enwerem

Abstract

Large studies on bedaquiline used to treat multidrug-resistant (MDR-) and extensively drug-resistant tuberculosis (XDR-TB) are lacking. This study aimed to evaluate the safety and effectiveness of bedaquiline-containing regimens in a large, retrospective, observational study conducted in 25 centres ...

Subject

Medicine

Bedaquiline

Tuberculosis

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