Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

C. Tsoi, Lam; E. Stuart, Philip; Tian, Chao; E. Guðjónsson, Jóhann; Das, Sayantan; Zawistowski, Matthew; Ellinghaus, Eva; N. Barker, Jonathan; Chandran, Vinod; Dand, Nick; Callis Duffin, Kristina; Enerbäck, Charlotta; Esko, Tõnu; Franke, André; D. Gladman, Dafna; Hoffmann, Per; Kingo, Külli; Kõks, Sulev; G. Krueger, Gerald; W. Lim, Henry; Metspalu, Andres; Mrowietz, Ulrich; Mucha, Sören; Rahman, Proton; Reis, André; Tejasvi, Trilokraj; C. Trembath, Richard; J. Voorhees, John; Weidinger, Stephan; Weichenthal, Michael; Wen, Xiaoquan; Eriksson, Nicholas; Min Kang, Hyun; A. Hinds, David; P. Nair, Rajan; R. Abecasis, Gonçalo; T Elder, James

doi:10.1038/ncomms15382

Public

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

Published in Nature Communications • May 24, 2017

Authors:

Lam C. Tsoi

Philip E. Stuart

Chao Tian

Abstract

Abstract Psoriasis is a complex disease of skin with a prevalence of about 2%. We conducted the largest meta-analysis of genome-wide association studies (GWAS) for psoriasis to date, including data from eight different Caucasian cohorts, with a combined effective sample size >39,000 individuals. We ...

Subject

Psoriasis

Genome-wide association study

Genetic architecture

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!