Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, Anubha; Wessel, Jennifer; M. Willems, Sara; Zhao, Wei; R. Robertson, Neil; Y. Chu, Audrey; Gan, Wei; Kitajima, Hidetoshi; Taliun, Daniel; William Rayner, N.; Guo, Xiuqing; Lu, Yingchang; Li, Man; A. Jensen, Richard; Hu, Yao; Huo, Shaofeng; K. Lohman, Kurt; Zhang, Weihua; P. Cook, James; Peter Prins, Bram; Flannick, Jason; Grarup, Niels; Vladimirovich Trubetskoy, Vassily; Kravic, Jasmina; Jin Kim, Young; V. Rybin, Denis; Yaghootkar, Hanieh; Müller-Nurasyid, Martina; Meidtner, Karina; Li-Gao, Ruifang; V. Varga, Tibor; Marten, Jonathan; Li, Jin; Vernon Smith, Albert; An, Ping; Ligthart, Symen; Gustafsson, Stefan; Malerba, Giovanni; Demirkan, Ayse; Fernandez Tajes, Juan; Steinthorsdottir, Valgerdur; Wuttke, Matthias; Lecoeur, Cécile; Preuss, Michael; F. Bielak, Lawrence; Graff, Marielisa; M. Highland, Heather; E. Justice, Anne; J. Liu, Dajiang; Marouli, Eirini; Marie Peloso, Gina; R. Warren, Helen; Consortium, ExomeBP; Consortium, MAGIC; Consortium, GIANT; Afaq, Saima; Afzal, Shoaib; Ahlqvist, Emma; Almgren, Peter; Amin, Najaf; B. Bang, Lia; G. Bertoni, Alain; Bombieri, Cristina; Bork-Jensen, Jette; Brandslund, Ivan; A. Brody, Jennifer; P. Burtt, Noël; Canouil, Mickaël; Ida Chen, Yii-Der; Shin Cho, Yoon; Christensen, Cramer; V. Eastwood, Sophie; Eckardt, Kai-Uwe; Fischer, Krista; Gambaro, Giovanni; Giedraitis, Vilmantas; L. Grove, Megan; G. de Haan, Hugoline; Hackinger, Sophie; Hai, Yang; Han, Sohee; Tybjærg-Hansen, Anne; Hivert, Marie-France; Isomaa, Bo; Jäger, Susanne; E. Jørgensen, Marit; Jørgensen, Torben; Käräjämäki, Annemari; Kim, Bong-Jo; Soo Kim, Sung; A. Koistinen, Heikki; Kovacs, Peter; Kriebel, Jennifer; Kronenberg, Florian; Läll, Kristi; A. Lange, Leslie; Lee, Jung-Jin; Lehne, Benjamin; Li, Huaixing; Lin, Keng-Hung; Linneberg, Allan; Liu, Ching-Ti; Liu, Jun; Loh, Marie; Mägi, Reedik; Mamakou, Vasiliki; McKean-Cowdin, Roberta; Nadkarni, Girish; Neville, Matt; F. Nielsen, Sune; Ntalla, Ioanna; A. Peyser, Patricia; Rathmann, Wolfgang; Rice, Kenneth; S. Rich, Stephen; Rode, Line; Rolandsson, Olov; Schönherr, Sebastian; Selvin, Elizabeth; S. Small, Kerrin; Stančáková, Alena; Surendran, Praveen; D. Taylor, Kent; M. Teslovich, Tanya; Thorand, Barbara; Thorleifsson, Gudmar; Tin, Adrienne; Tönjes, Anke; Varbo, Anette; R. Witte, Daniel; R. Wood, Andrew; Yajnik, Pranav; Yao, Jie; Yengo, Loïc; Young, Robin; Amouyel, Philippe; Boeing, Heiner; Boerwinkle, Eric; P. Bottinger, Erwin; Chowdhury, Rajiv; S. Collins, Francis; Dedoussis, George; Dehghan, Abbas; Deloukas, Panos; M. Ferrario, Marco; Ferrières, Jean; C. Florez, Jose; Frossard, Philippe; Gudnason, Vilmundur; B. Harris, Tamara; R. Heckbert, Susan; M. M. Howson, Joanna; Ingelsson, Martin; Kathiresan, Sekar; Kee, Frank; Kuusisto, Johanna; Langenberg, Claudia; J. Launer, Lenore; M. Lindgren, Cecilia; Männistö, Satu; Meitinger, Thomas; Melander, Olle; L. Mohlke, Karen; Moitry, Marie; D. Morris, Andrew; D. Murray, Alison; de Mutsert, Renée; Orho-Melander, Marju; R. Owen, Katharine; Perola, Markus; Peters, Annette; A. Province, Michael; Rasheed, Asif; M. Ridker, Paul; Rivadineira, Fernando; R. Rosendaal, Frits; H. Rosengren, Anders; Salomaa, Veikko; H.-H. Sheu, Wayne; Sladek, Rob; H. Smith, Blair; Strauch, Konstantin; G. Uitterlinden, André; Varma, Rohit; J. Willer, Cristen; Blüher, Matthias; S. Butterworth, Adam; Campbell Chambers, John; I. Chasman, Daniel; Danesh, John; van Duijn, Cornelia; Dupuis, Josée; H. Franco, Oscar; W. Franks, Paul; Froguel, Philippe; Grallert, Harald; Groop, Leif; Han, Bok-Ghee; Hansen, Torben; T. Hattersley, Andrew

doi:10.1038/s41588-018-0084-1

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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Shared by NobleBlocks on Apr 1, 2018 • 12:00 AM UTC

Authors:

Anubha Mahajan

Jennifer Wessel

Sara M. Willems

Research Assistant

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