Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice

Chen, Yi; Wang, Lei; Kang, Qiuxiang; Zhang, Xu; Yu, Guifang; Wan, Xiaojian; Wang, Jiafeng; Zhu, Keming

doi:10.1159/000477308

Public

Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice

Published in Cellular Physiology and Biochemistry • Jan 1, 2017

Authors:

Yi Chen

Lei Wang

Qiuxiang Kang

Abstract

BACKGROUND: Pulmonary endothelial injury is a critical process in the pathogenesis of acute lung injury (ALI) during sepsis. Heat shock protein A12B (HSPA12B) is mainly expressed in endothelial cells and protects against several harmful factors. However, the effects of HSPA12B in sepsis-induced ALI ...

Subject

Sepsis

Heat shock protein

Lung

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