Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

Carreras‐Torres, Robert; Johansson, Mattias; Haycock, Philip; H. Wade, Kaitlin; L. Relton, Caroline; M. Martin, Richard; Davey Smith, George; Albanes, Demetrius; C. Aldrich, Melinda; S. Andrew, Angeline; M. Arnold, Susanne; Bickeböller, Heike; E. Bojesen, Stig; Brunnström, Hans; Manjer, Jonas; Brüske, Irene; E. Caporaso, Neil; Chen, Chu; C. Christiani, David; Jay Christian, W.; A. Doherty, Jennifer; J. Duell, Eric; K. Field, John; P.A. Davies, Michael; W. Marcus, Michael; E. Goodman, Gary; Grankvist, Kjell; Haugen, Aage; Hong, Yun‐Chul; A. Kiemeney, Lambertus; H.F.M. van der Heijden, Erik; Kraft, Peter; B. Johansson, Mikael; Lam, Stephen; Teresa Landi, Maria; Lazarus, Philip; Le Marchand, Loı̈c; Liu, Geoffrey; Melander, Olle; L. Park, Sungshim; Rennert, Gad; Risch, Angela; B. Haura, Eric; Scélo, Ghislaine; Заридзе, Давид; Mukeriya, Anush; Savić, Milan; Lissowska, Jolanta; Świątkowska, Beata; Janout, Vladimí­r; Holcátová, Ivana; Mateș, Dana; B. Schabath, Matthew; Shen, Hongbing; Tardón, Adonina; Dawn Teare, M.; J. Woll, Penella; Tsao, Ming‐Sound; Wu, Xifeng; Yuan, Jian‐Min; J. Hung, Rayjean; I. Amos, Christopher; McKay, James; Brennan, Paul

doi:10.1371/journal.pone.0177875

Public

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

Published in PLoS ONE • Jun 8, 2017

Authors:

Robert Carreras‐Torres

Mattias Johansson

Philip Haycock

Abstract

BACKGROUND: Assessing the relationship between lung cancer and metabolic conditions is challenging because of the confounding effect of tobacco. Mendelian randomization (MR), or the use of genetic instrumental variables to assess causality, may help to identify the metabolic drivers of lung cancer. ...

Subject

Mendelian randomization

Obesity

Lung cancer

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!