Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters

Yu, Xinzhe; Yang, Guanghui; Yan, Chuangye; L. Baylon, Javier; Jiang, Jing; He, Fan; Lu, Guifeng; Hasegawa, Kazuya; Okumura, Hideo; Wang, Tingliang; Tajkhorshid, Emad; Li, Shuo; Yan, Nieng

doi:10.1038/cr.2017.83

Public

Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters

Published in Cell Research • Jun 16, 2017

Authors:

Xinzhe Yu

Guanghui Yang

Chuangye Yan

Abstract

The Escherichia coli uracil:proton symporter UraA is a prototypical member of the nucleobase/ascorbate transporter (NAT) or nucleobase/cation symporter 2 (NCS2) family, which corresponds to the human solute carrier family SLC23. UraA consists of 14 transmembrane segments (TMs) that are organized int...

Subject

Symporter

Dimer

Transporter

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