Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non–Small Cell Lung Cancer Using Next-Generation Sequencing

Jin, Xiance; Chen, Yanfan; Chen, Hanbin; Fei, Shaoran; Chen, Didi; Cai, Xiaona; Liu, Linger; Lin, Baochai; Su, Huafang; Zhao, Lihao; Su, Meng; Pan, Huanle; Shen, Lanxiao; Xie, Deyao; Xie, Congying

doi:10.1158/1078-0432.ccr-17-0577

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Evaluation of Tumor-Derived Exosomal miRNA as Potential Diagnostic Biomarkers for Early-Stage Non–Small Cell Lung Cancer Using Next-Generation Sequencing

Published in Clinical Cancer Research • Jun 12, 2017

Authors:

Xiance Jin

Yanfan Chen

Hanbin Chen

Abstract

Abstract Purpose: To identify tumor-derived exosomal biomarkers that are able to discriminate between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in the early diagnosis of non–small cell lung cancer (NSCLC). Experimental Design: Tumor-derived exosomes from the plasma of ...

Subject

Stage (stratigraphy)

Lung cancer

microRNA

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