First and second trimester serum tests with and without first trimester ultrasound tests for Down's syndrome screening

Kate Alldred, S; Takwoingi, Yemisi; Guo, Boliang; Pennant, Mary; J Deeks, Jonathan; P Neilson, James; Alfirević, Žarko

doi:10.1002/14651858.cd012599

Public

First and second trimester serum tests with and without first trimester ultrasound tests for Down's syndrome screening

Published in Cochrane Database of Systematic Reviews • Mar 15, 2017

Authors:

S Kate Alldred

Yemisi Takwoingi

Boliang Guo

Abstract

BACKGROUND: Down's syndrome occurs when a person has three copies of chromosome 21 (or the specific area of chromosome 21 implicated in causing Down's syndrome) rather than two. It is the commonest congenital cause of mental disability. Non-invasive screening based on biochemical analysis of materna...

Subject

Medicine

Down syndrome

Pregnancy

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