DNA methylation markers for diagnosis and prognosis of common cancers

Hao, Xiaoke; Luo, Hui; Krawczyk, Michał; Wei, Wei; Wang, Wenqiu; Wang, Juan; Flagg, Ken; Hou, Jiayi; Zhang, Heng; Yi, Shaohua; Jafari, Maryam; Lin, Danni; Chung, Christopher; Adam Caughey, Bennett; Li, Gen; Dhar, Debanjan; Y. Shi, William; Zheng, Lianghong; Hou, Rui; Zhu, Jie; Zhao, Liang; Fu, Xin; Zhang, Edward; Zhang, Charlotte; Zhu, Jian‐Kang; Karin, Michael; Xu, Rui‐Hua; Zhang, Kang

doi:10.1073/pnas.1703577114

Public

DNA methylation markers for diagnosis and prognosis of common cancers

Published in Proceedings of the National Academy of Sciences • Jun 26, 2017

Authors:

Xiaoke Hao

Hui Luo

Michał Krawczyk

Abstract

The ability to identify a specific cancer using minimally invasive biopsy holds great promise for improving the diagnosis, treatment selection, and prediction of prognosis in cancer. Using whole-genome methylation data from The Cancer Genome Atlas (TCGA) and machine learning methods, we evaluated th...

Subject

DNA methylation

Methylation

DNA

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