Two alternative pathways for docosahexaenoic acid (DHA, 22:6n-3) biosynthesis are widespread among teleost fish

Oboh, Angela; Kabeya, Naoki; Carmona‐Antoñanzas, Greta; Filipe C. Castro, L.; R. Dick, James; R. Tocher, Douglas; Monroig, Óscar

doi:10.1038/s41598-017-04288-2

Public

Two alternative pathways for docosahexaenoic acid (DHA, 22:6n-3) biosynthesis are widespread among teleost fish

Published in Scientific Reports • Jun 14, 2017

Authors:

Angela Oboh

Naoki Kabeya

Greta Carmona‐Antoñanzas

Abstract

Abstract Docosahexaenoic acid (DHA) plays important physiological roles in vertebrates. Studies in rats and rainbow trout confirmed that DHA biosynthesis proceeds through the so-called “Sprecher pathway”, a biosynthetic process requiring a Δ6 desaturation of 24:5n−3 to 24:6n−3. Alternatively, some t...

Subject

FADS2

Docosahexaenoic acid

Biosynthesis

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