Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder.

BPF, Rutten; E, Vermetten; CH, Vinkers; G, Ursini; NP, Daskalakis; E, Pishva; Nijs L, de; LC, Houtepen; L, Eijssen; AE, Jaffe; G, Kenis; W, Viechtbauer; den Hove D, van; KG, Schraut; KP, Lesch; JE, Kleinman; TM, Hyde; DR, Weinberger; L, Schalkwyk; K, Lunnon; J, Mill; H, Cohen; R, Yehuda; DG, Baker; AX, Maihofer; CM, Nievergelt; E, Geuze; MPM, Boks

doi:10.1038/mp.2017.120

Public

Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder.

Shared by NobleBlocks on Jun 20, 2017 • 12:00 AM UTC

Authors:

Rutten BPF

Vermetten E

Vinkers CH

Abstract

In order to determine the impact of the epigenetic response to traumatic stress on post-traumatic stress disorder (PTSD), this study examined longitudinal changes of genome-wide blood DNA methylation profiles in relation to the development of PTSD symptoms in two prospective military cohorts (one di...

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