Standardized Nanomechanical Atomic Force Microscopy Procedure (SNAP) for Measuring Soft and Biological Samples

Schillers, Hermann; Rianna, Carmela; Schäpe, Jens; Luque, Tomás; Doschke, Holger; Wälte, Mike; J. Uriarte, Juan; Campillo, Noelia; Michanetzis, G; Bobrowska, Justyna; C. Dumitru, Andra; T. Herruzo, Elena; Bovio, Simone; Parot, Pierre; Galluzzi, Massimiliano; Podestà, Alessandro; Puricelli, Luca; Scheuring, Simon; F. Missirlis, Yannis; Garcı́a, Ricardo; Odorico, Michaël; Teulon, Jean‐Marie; Lafont, Frank; Lekka, Małgorzata; Rico, Félix; Rigato, Annafrancesca; Pellequer, Jean‐Luc; Oberleithner, Hans; Navajas, Daniel; Radmacher, Manfred

doi:10.1038/s41598-017-05383-0

Public

Standardized Nanomechanical Atomic Force Microscopy Procedure (SNAP) for Measuring Soft and Biological Samples

Published in Scientific Reports • Jul 5, 2017

Authors:

Hermann Schillers

Carmela Rianna

Jens Schäpe

Abstract

We present a procedure that allows a reliable determination of the elastic (Young's) modulus of soft samples, including living cells, by atomic force microscopy (AFM). The standardized nanomechanical AFM procedure (SNAP) ensures the precise adjustment of the AFM optical lever system, a prerequisite ...

Subject

Atomic force microscopy

Microscopy

Snap

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