Evaluation of spectral photon counting computed tomography K-edge imaging for determination of gold nanoparticle biodistribution in vivo

Si‐Mohamed, Salim; P. Cormode, David; Bar-Ness, Daniel; Sigovan, Monica; C. Naha, Pratap; Langlois, Jean‐Baptiste; Chalabreysse, Lara; Coulon, Philippe; Blevis, Ira; Roessl, Ewald; Erhard, Klaus; Boussel, Loïc; Douek, Philippe

doi:10.1039/c7nr01153a

Public

Evaluation of spectral photon counting computed tomography K-edge imaging for determination of gold nanoparticle biodistribution in vivo

Published in Nanoscale • Jan 1, 2017

Authors:

Salim Si‐Mohamed

David P. Cormode

Daniel Bar-Ness

Abstract

= 0.93). TEM results were in agreement with the imaging and ICP-OES in that much higher concentrations of AuNPs were observed in the liver, spleen, bone marrow and lymph nodes (mainly in macrophages). In conclusion, we found that SPCCT can be used for repetitive and non-invasive determination of the...

Subject

Biodistribution

Materials science

In vivo

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